The 6-week, placebo-controlled randomized clinical trial consisting of nicotine chewing gum included 255 adults seeking to quit smoking (131 nicotine gum, 124 placebo). The researchers investigated the results of temptation events with or without chewing gum.

Participants had a total of 2713 points of temptation plots, 46.0% (1248), which led to smoking (reported lapse). The pooled data showed that the use of nicotine gum reduced the odds of tipping over the placebo (OR = 0.45, 0.22-0.94).

Electronic cigarettes are twice as efficient as other NRTs

At the same time, a 2019 randomized trial conducted by Queen Mary University in London was supported by the National Institutes of Health, the Health Technology Assessment Program and the UK Cancer Research, which showed that e-cigarettes are The efficacy is almost twice that of other NRT (nicotine alternative smoking cessation methods).

Researchers tracked nearly 900 smokers' attempts to quit smoking. All adults who visited the NHS smoking cessation clinic were randomly divided into two groups. One group of patients received their choice of conventional nicotine replacement therapy (NRT), such as nicotine gum or patches (including product mix if needed), while the other group received e-cigarettes. In addition, behavioral support was provided to the two groups.

One year later, the smoking status of the participants was evaluated, including biochemical tests to ensure that the person who claimed to quit smoking did smoke. In a year, the withdrawal rate of the NRT group reached 9.9% a year, which is a surprisingly high level, because previous studies found that the withdrawal rate of NRT was only 5-7%. However, the success rate of the e-cigarette group is almost twice that of the latter, and the moderation rate is 18%.