Is Nicotine Harmful To The Body? The Answer May Surprise You.

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Is nicotine harmful to the body? The answer may surprise you.

March 6,2019.

Since e-cigarettes do not need to be burned, safe, healthy, and pollution-free, after the e-cigarettes enter China, the market is booming, the market is becoming more mature, and products are becoming more diversified. Consumers have created safety for e-cigarettes. Questioning that the most worrying thing in smoke oil is nicotine.
In everyone's perception, nicotine is very addictive, causes cancer, causes heart problems, hurts the brains of teenagers, etc. It has long been regarded as a threat. Even some countries have taken corresponding measures. For example, in Australia, all liquids containing nicotine are prohibited from being sold. As the most notorious compound in tobacco, it's easy to understand why nicotine is so embarrassed, but are these negative effects true? We can get a deeper understanding of nicotine and its impact on the body.
Nicotine basics

What is nicotine?
Nicotine, commonly known as "nicotine," is the most famous compound in tobacco. It is an alkaloid, which means it contains nitrogen, similar to chemicals such as caffeine and cocaine.
The source of nicotine?
In addition to being found in tobacco plants, nicotine is also found in potatoes, tomatoes and eggplants, in small quantities. A comparative analysis of their nicotine content found that about 1 mg of nicotine per 1 gram of tobacco, and 0.0001 mg of nicotine per 1 gram of eggplant, which is the highest nicotine content, with lower levels of tomato and potatoes.
How much nicotine does the cigarette contain?
Each cigarette usually contains about 10 mg of nicotine, but it is not actually absorbed. The process of burning, filtering, etc. will lose nicotine when smoking. In fact, only a small portion of nicotine can be absorbed by the body. Each cigarette only absorbs about 1 Mg of nicotine.

How is nicotine absorbed by the body
When you smoke, nicotine enters the bloodstream through the lungs and is absorbed by the body. Usually in an alkaline environment, nicotine enters the blood more efficiently, which is why tobacco companies adjust the composition of cigarettes to raise the pH (even if it is more alkaline). After reaching the bloodstream, nicotine enters your artery through the heart and turns to your brain. The entire process takes 10 to 20 seconds.
The situation of e-cigarettes is somewhat different. The Royal College of Physicians pointed out in its report that most of the nicotine produced by e-smokering is absorbed by the mouth and throat rather than by the lungs, although nicotine is absorbed in this way. It will still reach the blood, but it is obviously not as fast as when you smoke. This is one of the reasons why electronic cigarettes are more addictive than traditional cigarettes.
Nicotine effect
The role of nicotine is the result of its ability to bind certain receptors in the brain. When nicotine binds to nicotinic acetylcholine receptors (nACHRs) in the brain, it stimulates the release of "neurotransmitters." This is similar to the chemical messenger that the brain uses to send signals. Everyone knows dopamine, which plays a central role in the process of addiction, but it is a neurotransmitter that is often misunderstood. Dopamine is not the only neurotransmitter affected by nicotine. It also includes:
Serotonin: affects your mood GABA (gamma-aminobutyric acid): reduces neuronal activity glutamate: an "excitatory" neurotransmitter. Norepinephrine: known as "stress hormone."
These factors help explain the reasons for nicotine addiction. When nicotine regularly stimulates the nACHR receptor, the body reduces the number of receptors and reduces the response of acetylcholine itself, which means that the same amount of nicotine no longer has the same effect. If you don't take nicotine, your body will feel uncomfortable. Causes unpleasant symptoms such as anxiety, anxiety, and inability to concentrate after withdrawal. That's why when you quit smoking, alternative nicotine-derived methods such as e-cigarette or nicotine replacement therapy have a very significant effect, which alleviates these symptoms and makes the smoke-free transition smoother.

Is nicotine harmful?
"Nicotine is in tobacco, tobacco is not good for me, so nicotine is not good for me." This should be everyone's idea. Nicotine is the most important substance in cigarettes, but this does not mean that the harm in cigarettes comes from nicotine. The sentence is very good: "drinking nicotine but dying of tar."
Does nicotine induce cardiovascular disease? Lung health has done research: they conducted a study of hospitalized patients who used nicotine gum. The results showed that there was no connection between nicotine chewing gum use and cardiovascular problems, and most of the side effects reported in the study were mild. Other studies have shown similar results. A meta-analysis published in 2014 examined 21 different nicotine replacement therapy trials and found no clear evidence of heart and blood vessel risk. The snus user's research has similar results.
Despite this, there are still many uncertainties in this result. Overall, what is certain is that if nicotine does affect your heart problem, then the risk will be smaller than the way smoke is consumed, which is good news for e-cigarette users.
Another of the biggest misconceptions about nicotine is that it causes cancer, and the answer is that nicotine does not cause cancer at all. There is evidence that nicotine can promote tumor growth, but it does not actually cause cancer. Researchers in the Lung Health Study studied the population of smoking and nicotine patches and chewing gum for five years, by seven and a half years of follow-up, and concluded that although smoking is associated with cancer, the use of nicotine replacement therapy and cancer no connection.
to sum up
For people who use e-cigarettes, they are more worried about whether nicotine is harmful to humans? This is not an easy question to answer, but the shortest answer is "not true, or at least not very harmful." Caffeine, like nicotine, is a mild stimulant that has some short-term effects on the body, but excessive intake of nicotine can cause serious harm, ranging from dizziness to poisoning. Of course, addiction is a well-recognized fact. If you can't get rid of cigarettes, the culprit is nicotine, so nicotine therapy such as e-cigarettes is a good aid.