WARNING: THIS PRODUCT CONTAINS NICOTINE. NICOTINE IS AN ADDICTIVE CHEMICAL
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Third generation nicotinic insecticide

2019-11-25

Dinotefuramide belongs to the third generation of nicotine products. Since its launch in 2002, its excellent performance and annual sales have increased, making it exceed 100 million US dollars in 2011, in October 2014 in China. The patent expires. In the communication with the customer, the feedback field test effect is very good. If the price of the original drug can drop back to more than 300,000 yuan / ton, the price/performance ratio of the product will be very high, and it is expected that the performance in the rice region will be good. attention.


1 Classification of nicotine products
    First-generation nicotine products: imidacloprid (developed by Bayer in 1991), nitenpyram (developed in Takeda in 1995), acetamiprid (developed in Japan by Caoda in 1996), and thiacloprid (developed by Bayer in 2000). The intermediate is 2-chloro-5-chloromethylpyridine and belongs to the class of chloropyridines.


    Second-generation nicotine products: thiamethoxam (developed by Novartis in 1998), clothianidin (Bayer, 2002 developed by Takeda). The intermediate is 2-chloro-5-chloromethylthiazole and belongs to the class of chlorothiazoles.


    Third-generation nicotine products: dinotefuran (developed by Mitsui Chemicals in 2002), tetrahydrofuranyl substituted chloro group and free of halogen elements.


2 Physicochemical properties and mechanism of dinotefuran
    Physical and chemical properties: pure product is white crystal, melting point 107.5 ° C, solubility: water 40 g / L, difficult to dissolve in xylene, cyclohexane and other organic solvents.


    Mechanism of action: Dinotefuramide acts mainly on the insect neurotransmitter system, causing pests to cause paralysis and thereby exerting insecticidal effects. It is also a nicotinic acetylcholine receptor (nAChR) agonist, which not only has contact and stomach toxicity, but also has excellent systemic and osmotic effects, can be quickly absorbed by the roots and stems of plants, and is transmitted upward.


3 control objects
    Dinotefuran has a wide spectrum of insecticidal activity, and it can control various pests such as Hemiptera, Lepidoptera, Beetle, Diptera, Orthoptera, Hymenoptera.


    (1) Rice pests
    Efficient: brown planthopper, white-backed planthopper, gray planthopper, black-tailed spider mites, rice spider mites, two small star scorpions, rice green scorpion, red-streaked scorpion, rice negative worm, rice otter.


    (2) Vegetables, fruit pests
    Efficient: mites, white mites, mites, yam scorpion, vermilion, peach small heartworm, orange moth, tea moth, yellow stripe, bean fly.


    (3) Dinotefuran is superior to traditional nicotinic insecticides due to its special structure, not only on rice, vegetables, fruit trees, flowers, Hemiptera, Lepidoptera, Diptera, Beetle The eye and the total wing pest are highly efficient and highly effective against sanitary pests.
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