WARNING: THIS PRODUCT CONTAINS NICOTINE. NICOTINE IS AN ADDICTIVE CHEMICAL
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What is the effect of nicotine on the body?

2019-11-26

How is nicotine absorbed by the body

When you smoke, nicotine enters the bloodstream through the lungs and is absorbed by the body. Usually in an alkaline environment, nicotine enters the blood more efficiently, which is why tobacco companies adjust the composition of cigarettes to raise the pH (even if it is more alkaline). After reaching the bloodstream, nicotine enters your artery through the heart and turns to your brain. The entire process takes 10 to 20 seconds.
The situation of e-cigarettes is somewhat different. The Royal College of Physicians pointed out in its report that most of the nicotine produced by e-smokering is absorbed by the mouth and throat rather than by the lungs, although nicotine is absorbed in this way. It will still reach the blood, but it is obviously not as fast as when you smoke. This is one of the reasons why electronic cigarettes are more addictive than traditional cigarettes.


Nicotine effect

The role of nicotine is the result of its ability to bind certain receptors in the brain. When nicotine binds to nicotinic acetylcholine receptors (nACHRs) in the brain, it stimulates the release of "neurotransmitters." This is similar to the chemical messenger used by the brain to send signals. Everyone knows dopamine, which plays a central role in the process of addiction, but it is a neurotransmitter that is often misunderstood. Dopamine is not the only neurotransmitter affected by nicotine. It also includes:

Serotonin: affects your mood GABA (gamma-aminobutyric acid): reduces neuronal activity glutamate: an "excitatory" neurotransmitter. Norepinephrine: known as "stress hormone."


These factors help explain the reasons for nicotine addiction. When nicotine regularly stimulates the nACHR receptor, the body reduces the number of receptors and reduces the response of acetylcholine itself, which means that the same amount of nicotine no longer has the same effect. If you don't take nicotine, your body will feel uncomfortable. Causes unpleasant symptoms such as anxiety, anxiety, and inability to concentrate after withdrawal. That's why when you quit smoking, alternative nicotine-derived methods such as e-cigarette or nicotine replacement therapy have a very significant effect, which alleviates these symptoms and makes the smoke-free transition smoother.


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